怎么,commonly used to inquire about the situation, nature, way, cause, question, action, etc., commonly used as a question language.
Ask for nature, manner, cause, action, etc.
他们怎么还不回来?ta men zen me hai bu hui lai
Why aren't they back?
Used for virtual reference ,refers to an event.
不知怎么,她很气恼 bu zhi zen me ta hen qi nao
Don't know why, she's angry.
stands for degree
也许它留给你的印象不怎么深 ye xu ta gei ni liu xia de yin xiang bu zen me shen
Perhaps it left you with a less impressive impression
Stands for anyway,in any case
我怎么也猜不透 wo zen me ye cai bu tou
I can't guess in any guess
(My English is poor ,I don't know if you can read my writing.)