The word "तु,तुम,and तुमसे" is use for child & younger person & आप and आपको is use for elder person and in respect sence .

मैं तुमसे नाराज हूँ

i am angry with u means in hindi is.......................main tumse gussa hoon

" main aap se naraaj hun ".....i am angry with you

u can say that "mein tumse bahut gussa hu"