실제로 in real , in fact
실은 less formal, casual form
실제 noun, it comes by itself or with another noun to explain that it happened real. For example 이론과 실제 (theory and reality) or 실제 상황
실로 similar with 실은 but it could be used in the newspaper, not commonly used when you talk
사실상 it’s more like ‘actually’. When you explained something and it turned out differently or sth like that.