so let’s look at both sentences.
When Americans say sorry, they mostly mean it.
-This means that when Americans say sorry, they usually mean it; or they mean it, but not wholeheartedly.
But, at least to British ears, they (Americans) don’t necessarily mean anything else they say.
-This means that British people don’t think Americans mean what they say all the time. They might mean it, and they might not. So what an American says might be true, or it might not.
Hope that helps :)