They are utterly different and can't be compared.
Extremely - adverb = very
Witless - adjective = without wits. (Wits are the ability to think clearly.)
We were very bored.
We were so bored that we were without wits.
August 7, 2023
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Say #2 in informal conversation only. It is colloquial.
August 8, 2023
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Bored witless is a fixed expression. I can’t really think of another use for witless.
August 7, 2023
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