Native English speakers would pronounce 'Skype' to rhyme with 'type', and 'Waze' to rhyme with 'days'.
The final 'e' is silent. It isn't a separate syllable. The function of the letter 'e' at the end is to make the vowel longer - as in the difference between the words 'hat' and 'hate'.
The only times where an 'e' at the end is pronounced as a separate syllable are names and words taken from other languages - the country 'Chile' for example.