Literally '피가 시퍼런 인간' means 'a man(or woman) who has [blue] blood'.
시퍼런 is quite strong expression of '파란(blue)'. It has rough, severe and strong feelings.
In this case, 피가 시퍼런 is 'cold-blooded'. 'cold-hearted'.
So, the person felt 'he is a true cold-blooded person, it seems he doesn't even catch a cold'.