"The math matriculation exam gave me cancer." Note: it is not "a cancer" in this case. While the other two answers are correct, I'll try to be more detailed. Since you cannot actually get cancer from taking an exam, the phrase means that the exam was so bad that it does not follow logic and gave the speaker a terrible illness anyway. This is actually a very rude and juvenile thing to say so please be careful if you borrow this phrase. Similarly, people will say "this exam gave me AIDS" or "that TV show is AIDS." I'm sure you can replace AIDS and cancer with other diseases, but they are far less common. Again, this is not something you should repeat in good company. This can be confused with "like cancer" or "spreads like cancer," e.g. "the rumours spread like cancer." This would mean that the rumours spread quickly, quietly, and they are dangerous, similar to how cancer spreads. Let me know if this explains it for you!

It means that the exam was horrible.

MATH：Mental Abuse To Human Means math exam kills you.

OK