Sometimes yes, sometimes no.
If you are talking about vegetables as a concept, then no.
For example:
I like vegetables.
Vegetables are healthy.
A good source of vitamins are vegetables.
If you are talking about vegetables in a more specific way, than yes.
For example:
Please put the vegetables on the table.
The vegetables are almost done cooking.
I looked for the vegetables in the refrigerator.
Good luck!
祝你好运