Oh, what the hell...
Blanche has a nervous breakdown after being attacked and supposedly raped by Stanley. The rape is never definitely confirmed in the play, but implied strongly. Given Stanley's animalistic brutality, it is usually assumed that the rape actually happed, even though Stella refused to believe it.
Blanche is committed to a mental institution, being now totally immersed in her fantasy world and severing all ties with reality. This is where Blanche delivers her famous line about depending on the kindness of strangers.