You see the same root in both words.
Creature, refers to a living organism, either plant, animal, human being, or even bacteria.
Creation, can refer to both living and non-living, or animate and inanimate identities.
Creation, in the broadest context, refers to everything in the Universe. The term Universe, is an older term. The modern term for "everthing" is Cosmos.
The Cosmos, called a "creation" in the spiritual or metaphysical context, is all that has "come into" existence since the Moment---of---Singularity associated with the Scientific Theory of the Big Bang.
The distinction must be indicated, that there is a difference between identities that are MADE, and those which are CREATED. Identities which are MADE, are constructed from pre-existing material. For example, a clay pot, is made from clay, that already exists.
CREATED identities (such as the Cosmos) however, can be understood to be identities which come from a non-existent identity.
The great question in philosophy, and also in Science, is how can the "creation" come from what is apparently, "nothing". The great knowledge that Science gives mankind, is that all that exists, "comes into being" or has an identifiable Cause.
This answer stops at the Moment---of---Singularity. We cannot see what the Cause of the
"Creation" (Cosmos) is. So, we have a great mystery.
Usually, the answer is offered in the form of a Logical Proof, rather than an Empirical demonstration. Logically, the Cause or Creator is referred to as Mind, God, and so forth, because it would be unscientific to say something like, Matter---Caused----Itself. That is a redundant statement.