I agree with the Spanish girl and Venezuelian guy.
You can say like this:
1. Me parece + Que + estar + adjective (literally: You seem like to be very tired)
Estar: estoy, estás, está, estamos, estaís, están
2. Te veo + adjective (it is simplier to you... Te veo muy cansado - literally: I see you very tired).
You can choose what you wanna use. I hope it was helpful to you.