No, they are used differently.
'Don't get me wrong' is essentially saying "Don't misunderstand what I am saying, or what I just said".
"He gets into trouble sometimes, but don't get me wrong, he's still a good boy".
'Make no mistake' stresses the truth or fact of what you are about to say.
"He gets into trouble sometimes, and make no mistake, he'll end up in prison if he's not careful."