Yes. Depending on the context it was used in, “humor me” can mean something like “tell me anyway”.
You use “humor me” when you’re asking someone to do something for you just to keep you happy. It kind of means “don’t argue with me about this, just do it.”
For example, say you’re having a conversation with someone and you’re about to tell them your opinion on something. They don’t want to hear it, so you say something like “I know you don’t want to hear this but just humor me, okay?”
Also, if someone asks you an obvious question (which they probably already know the answer to) they might say “humor me” to mean “I already know what your answer will be, but tell me anyway because I want to make sure.”