There may be some overlap in the meaning and use of these phrases. Both could be used to suggest a manager or "boss". Both could also relate to roles and tasks required in jobs. "in charge of" implies more authority and an older style of management. "responsible for" is perhaps more modern and a softer way of expressing a management role. There is some freedom to use either depending on the style or context.

They are closely synonymous. If you are "in charge of" something or someone, you were probably appointed to take on a responsibility in a more formal way than if you are simply "responsible for" it or them.

To be responsible for doing something - it's your job to do something. To be in charge of doing something - you manage the 'something'. You may do it yourself and/or supervise other staff doing it. i.e. I was responsible for opening the post.= I opened the post. I was in charge of opening the post = I may have done it myself but I probably also managed the post in some way, and probably supervised others who opened the post.

I am in charge of my subordinates at work. I am able to give them orders, and make decisions regarding what they do, and how they do it. I am responsible for my children. I must ensure their safety and care.Their behavior is a reflection of the decisions I made while raising them. I must answer for their health and behavior both in the home and outside the home, good or bad. The two words can be used interchangeably, but "responsible for" implies a level of personal ownership, and may include legal responsibility. "In charge of" implies a legal responsibility, but not necessarily any personal ownership.

- In charge of: you have an official position or capacity over something. - responsible for: you have a duty, authority, or obligation for something, official or not. So "responsible for" is much more widely used for all kinds of situations. ex) - I am in charge of this department. (role, capacity, position) - I am in charge of making sure everyone is safe. - I am responsible for this department. (duty, capacity) - I am responsible for my own actions. (moral obligation) - I am responsible for the window I broke. (same)