This phrasal verb has many, many meanings. 1. flee - They wanted to run off before the trouble started. 2. print or make photocopies - He ran off two-hundred advertisements. 3. write something in a hurry - She could run off an essay at a moment's notice. 4. spill - Rainwater ran off the roof. 5. leave without notice - Her husband ran off to France. 6. operate from a source of power - The computer runs off batteries. 7. chase someone or something away - If anyone comes, run them off. 8. run off at the mouth - talk without ceasing 9. run off with someone - leave in the company of someone with the intention of marriage or cohabitation.

1 run away ; 2 reprint ; 3 A last PK

Run off sometimes refers to water or chemicals that spills. For example, During the rain storm the run off went into the ocean.