How to say, "have a safe trip!" In korean to a friend
Informally to a friend who is travelling a long distance, like wishing them well on their adventure to another place

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잘 다녀와! - This might me the correct answer. We don't use '안전하다' in this case.
잘 다녀와 literally means "go and return well." But it include safety and having a good time.

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"Have a safe trip!" => 별일 없이 잘 도착하기 바라 (Hope you get there without trouble) / 안전한 여행 되기 바라.

Answer

잘 가십시오.