Does this sentence make sense?or are there better ways to express it? thank you sooo much!
I love helping people who are in need

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If it had a period at the end of the sentence, it would be perfect.  Punctuation is important.

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I would say "I love helping people in need."

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thank you :) I just want to make sure I use it in a natural way

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thank you :) I just want to make sure I use it in a natural way

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Evidently your sentence makes sense and I like it so much.