You and I are friends. You are a friend to me. He is a friend. I am friends with him.

"You and I are friends." is correct. You'll hear native speaks say "You and me" or even "Me and you". These are both incorrect. "I" is a subject pronoun. "Me" is a direct,indirect, or disjunctive pronoun. It cannot act as a subject unless you are talking thereabout as a word (like what I did in the last sentence.)

I think both are right, but the first one is more correct becasue you use the pronoun 'I' before the verb ''to be'' It's like you say ''you are my friend'' ''I am your friend'' = we are both friends = you and I are friends

You and I are friends. You and me are friends. Both these phrases are correct. The use of "me" in this context is too complicated to explain. But it is correct.

You and I are friends First Subject + Second Subject + Verb + Complement ----- Correct You and Me are friends Subject + Object + Verb + Complement ------ Incorrect Because before the verb is always the subject and the subjective personal pronouns are You and I not You and Me because Me is an objective pronoun The Best Friends are You and Me ------ Correct Article + Adjective + Subject + Verb + First Object + Second Object I hope this helps :)