Which one is ok?
I have never been more sure of anything in my entire life.
I have never been more sure about anything in my entire life.

Question

Answer

In this particular case, both "of" and "about" are correct, you can choose either. "About" sounds more natural and casual, but both are definitely okay. There are many other circumstances where these two words' meanings are quite different, so be careful!

Answer

The second one would be correct however, the best way to struct that sentence is to change "sure" to "certain."

-->  I have never been more certain about anything in my entire life.

But either one would be fine. :)

Answer

Both sound fine :) Maybe the second one sounds a LITTLE tiny bit better, but both are really okay.

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