All of the words refer to taking care of something. They only differ in the situation in which they're used. When I hear "cope with", I think about someone dealing with something like an illness or a difficult situation. Ex: He's coping with his mother's passing very well. "Handle" is simply taking care of a situation. Ex: He's handling his new responsibilities at work with ease. An alternate definition of "handle" can be a grip attached to an object for using or moving the object, such as a door handle. You can also "handle" objects. "Tackling" a situation implies that you're taking care of the situation with enthusiasm or vigor. Ex: He tackled the project full-force and had it done by yesterday afternoon. Using "address" is similar to using "handle" in that you're simply taking care of the situation. Ex: She addressed the grieving mother with grace.

Cope with = manage cope with : to deal successfully with sth difficult Examples : I got to the stage where I wasn’t coping any more. He wasn’t able to cope with the stresses and strains of the job. Desert plants are adapted to cope with extreme heat. ............................ Handle = deal with Handle : to deal with a situation, a person, an area of work or a strong emotion Examples : A new man was appointed to handle the crisis. She’s very good at handling her patients. The sale was handled by Adams Commercial. We can handle up to 500 calls an hour at our new offices. ................................................ Tackle : 1-to deal with sb who is violent or threatening you Example: He tackled a masked intruder at his home. 2- to make a determined effort to deal with a difficult problem or situation Example : The government is determined to tackle inflation. ........................................................ Address a formal speech that is made in front of an audience Example : tonight’s televised presidential address ................. Source : Oxford Advanced Learner's Dictionary